Milwaukee at NY Yankees 1:05 PM ET
Max Fried was the big starting pitching acquisition for the New York Yankees. For the Milwaukee Brewers, it was Nestor Cortes, who spent five seasons in Yankee pinstripes.
LA Angels at Chi. White Sox 2:10 PM ET
Chicago White Sox catcher Korey Lee finds it refreshing to be on the plus side of .500 after one game, especially after the club endured a modern-day record 121 losses in 2024.
Minnesota at St. Louis 2:15 PM ET
Joe Ryan could make a big difference in the Minnesota Twins' starting rotation this season, provided he returns to form after recovering from a shoulder injury.
Baltimore at Toronto 3:07 PM ET
Toronto's Max Scherzer was given the thumbs up to start Saturday afternoon against the visiting Baltimore Orioles. Now the Blue Jays hope his thumb holds up.
Philadelphia at Washington 4:05 PM ET
Left-hander Jesus Luzardo makes his Phillies debut when Philadelphia visits the Washington Nationals on Saturday.
San Francisco at Cincinnati 4:10 PM ET
A future Hall of Fame pitcher takes the mound to begin his 20th season when the visiting San Francisco Giants play the Cincinnati Reds in the second of a three-game series Saturday.
Colorado at Tampa Bay 4:10 PM ET
There was plenty of newness around Tampa Bay's Opening Day win on Friday, and the Rays will look to do it again Saturday afternoon in their second meeting with the visiting Colorado Rockies.
Pittsburgh at Miami 4:10 PM ET
Left-hander Bailey Falter, who is coming off perhaps the best season of his career, will start on Saturday afternoon as his Pittsburgh Pirates visit the Miami Marlins.
Cleveland at Kansas City 4:10 PM ET
The first seven seasons of Seth Lugo's stint in the majors weren't all that memorable.
Boston at Texas 7:05 PM ET
Walker Buehler is looking to revive his career by pitching a full season for the first time since 2021.
NY Mets at Houston 7:15 PM ET
left-hander Sean Manaea and right-hander Frankie Montas -- sidelined by injuries, the New York Mets were forced to piece together a rotation that didn't match the grand vision set after their offseason moves were completed.
Atlanta at San Diego 7:15 PM ET
For the San Diego Padres, the good news out of the first two games is their bullpen has allowed just one run in 11 innings and been responsible for two wins over the visiting Atlanta Braves.
Chi. Cubs at Arizona 8:10 PM ET
Arizona right-hander Brandon Pfaadt will make his first start of the 2025 season with the security of a new multi-year contract when the Diamondbacks host the Chicago Cubs on Saturday in Phoenix.
Detroit at LA Dodgers 9:10 PM ET
After feeling the love in his home country while making his major league debut, rookie right-hander Roki Sasaki now will get plenty of support from his new home fans when the Los Angeles Dodgers try for a series sweep against the Detroit Tigers on Saturday.
Athletics at Seattle 9:40 PM ET
Near the end of a news conference announcing catcher Cal Raleigh's six-year, $105 million contract extension with the Seattle Mariners on Friday afternoon, a question came from the back row.