OAKLAND, Calif. -- Guard Klay Thompson scored 42 points, leading the Golden State Warriors to a 111-107 victory against the Memphis Grizzlies on Monday night at Oracle Arena.

The Warriors (66-15) won their 17th straight home game and struck a painful blow to Grizzlies' hopes of landing the No. 2 playoff seed in the Western Conference or winning the Southwest Division.

Guard Stephen Curry scored 15 points for the Warriors, who have clinched the Pacific Division and the No. 1 seed in the West.

Guard Jordan Adams came off the bench to lead Memphis (54-27) with 19 points. Guard Russ Smith had 16 points off the bench, and forwards Zach Randolph and JaMychal Green scored 10 apiece

Thompson shot 15-for-21 from the field, made 8 of 10 from beyond the arc and hit all four of his free-throw attempts. He had his fourth career 40-point game.

Thompson scored 37 points in the first half, leading the Warriors to a 68-46 lead. Thompson made his first eight shots of the game, including all three from long range, and finished 14 of 17 from the field, 7 of 8 from beyond the arc and 2 of 2 from the line in the opening half.

Thompson had 11 points in the first quarter, making all four shots, and added 25 in the second, showing shades of his record-setting third quarter against the Sacramento Kings on Jan. 3. He scored 37 points in the third that night -- the most in any quarter in NBA history -- going 13-for-13 from the field, 9-for-9 from 3-point range and 2-for-2 from the line.

Thompson scored a career-high 52 points against Sacramento and set an NBA record for 3-point baskets in a quarter that game.

The Warriors extended their lead to 82-52 when Thompson made a 3-point shot with 6:36 left in the third period. They led 93-66 entering the fourth quarter, and Thompson had 42 points.

Thompson and most of Golden State's starters sat out the fourth quarter as Memphis, powered primarily by its reserves, made the Warriors sweat. The Grizzlies cut Golden State's lead to 110-106 with 13.7 seconds left and 111-107 with 8.0 remaining.

Center Marc Gasol started for Memphis, despite spraining his left ankle Saturday against the Clippers in the first quarter and leaving the game, but scored just six points. Grizzlies guard Mike Conley (sprained right foot) and swingman Tony Allen (strained left hamstring) were both out, leaving the Grizzlies short-handed.

Golden State won the season series 2-1.

NOTES: Grizzlies C Marc Gasol was listed as questionable for Monday night's game against Golden State with a sprained left ankle but was in the starting lineup. Gasol was injured in the first quarter Saturday against the Clippers and did not return to that game. ... Memphis G Mike Conley missed his third straight game with a sprained right foot. He's averaging 15.8 points and a team-high 5.4 assists. ... Grizzlies G Tony Allen missed his seventh straight game with a strained left hamstring. ... Memphis F Jeff Green (lower back tightness) started against the Warriors. ... Warriors G Leandro Barbosa (sore right Achilles) was active for Monday's game. ... Thanks in part to so many blowout wins this season, Warriors G Stephen Curry was averaging only 32.9 minutes per game and G Klay Thompson 32.1 minutes going into Monday's game. Warriors coach Steve Kerr said he'd like to increase their playing time in the final games to prepare them to play more minutes in the playoffs. "You always have to counter that with concerns about injuries, but injuries can happen slipping in the shower," Kerr said.