Fernando Tatis Jr. capped a three-run seventh inning with a two-run homer Friday afternoon, leading the San Diego Padres to a 5-3 victory at St. Louis in the Cardinals' home opener.

The homer by the 20-year-old rookie -- whose father, Fernando Tatis, played three seasons for the Cardinals -- followed a tiebreaking sacrifice fly by Franchy Cordero.

Manny Machado and Franmil Reyes opened the rally by drawing back-to-back walks from Alex Reyes (0-1), and both advanced on a wild pitch. After Wil Myers grounded out, Machado scored on Cordero's fly to center fielder Harrison Bader. Tatis followed with a homer to left.

An inning earlier, pinch hitter Hunter Renfroe also hit a two-run homer to left off St. Louis reliever Dominic Leone to give the Padres a 2-1 lead. Cordero's leadoff walk preceded Renfroe's third homer in a span of nine at-bats.

Paul DeJong's solo homer with one out in the fourth was the only hit off Padres rookie starter Nick Margevicius, who was involved in an unusual pitching duel with Cardinals right-hander Jack Flaherty.

Margevicius allowed the one run and one walk while striking out one over five innings. Flaherty stranded Padres at third in four consecutive innings over five shutout innings. He allowed six hits and two walks with six strikeouts.

The Cardinals tied the game in the bottom of the sixth immediately after Renfroe's homer. Matt Carpenter had a one-out double fall between Padres outfielders in right-center, and he scored on Marcell Ozuna's two-out single to right off Robert Stock.

Paul Goldschmidt hit his fifth homer in seven games as a Cardinal in the eighth off right-hander Trey Wingenter to narrow the Padres' lead to 5-3.

Stock (1-0) got credit for the win despite allowing one run in one inning. Kirby Yates picked up his fourth save after throwing a scoreless ninth. Five San Diego pitchers held the Cardinals to four hits and six baserunners.

--Field Level Media