Athletics 6, Giants 2: Josh Reddick hit a two-run homer and visiting Oakland halted an 11-game losing streak at San Francisco's AT&T Park.

Collin Cowgill had a two-run single in a four-run fourth and bowled over Giants ace Tim Lincecum in a collision at home plate as the Athletics won in San Francisco for the first time since June 15, 2008.

Bartolo Colon (4-4) ended a three-game losing streak, allowing two runs on six hits in five innings to earn his first win since April 18.

Lincecum (2-4) had another rocky outing, lasting only four innings and giving up four runs for the third consecutive start. He was plowed over on a headfirst slide by Cowgill, who scored from second base on a wild pitch.

The two-time National League Cy Young Award winner appeared to be hit in the face by Cowgill's helmet. He finished the inning and came out for a pinch hitter in the bottom of the frame.

Melky Cabrera went 4-for-4 and Joaquin Arias and Buster Posey had sacrifice flies to give the Giants a 2-0 lead after three innings.

Lincecum unraveled in the fourth, giving up two hits and a walk to load the bases before Kurt Suzuki delivered an RBI single and Cowgill followed with a two-run single.

Reddick hit his team-high 11th homer in the sixth off Giants reliever Shane Loux to stretch the lead to 6-2.

Jordan Norberto, Grant Balfour, Ryan Cook and Brian Fuentes each threw a scoreless inning of relief for the Athletics.

GAME NOTEBOOK: Giants CF Angel Pagan extended his hitting streak to 11 games. He has hit safely in 31 of the last 32 games. ... Oakland placed P Brandon McCarthy, the team's opening day starter, on the 15-day disabled list Sunday with a strained right shoulder. ... Cabrera had his third straight multi-hit game of the series and major league-best 20th of the season. ... It was the sixth time in nine starts that Lincecum has permitted at least four runs. ... Reddick was 0-for-9 in the series before launching his homer in the seventh. ... Manny Ramirez was held out of Sunday's game at Triple-A Sacramento due to a sore wrist. He went 0-for-4 and struck out three times Saturday in his first game. Ramirez is scheduled to make his Athletics debut May 30.