Tigers 7, Reds 6: Austin Jackson homered and highlighted a four-run eighth inning with a two-run double as visiting Detroit rallied to take the rubber game of the three-game interleague series.

Todd Frazier helped stake Cincinnati to a 6-2 lead with a two-run single in the second inning and a two-run homer in the sixth. But Prince Fielder's RBI single in the seventh got Detroit within three, and the Tigers moved ahead with their eighth-inning rally.

Ramon Santiago drew a leadoff walk from Logan Ondrusek and Gerald Laird followed with an infield single. Aroldis Chapman (4-2) came in and struggled, allowing a single by pinch hitter Brennan Boesch and hitting Matt Young with a pitch to force in a run.

Jackson, who belted a solo homer in the fifth, delivered a ground-rule double to tie the contest. After Quintin Berry walked to again fill the bases, Young raced home with the go-ahead run on a wild pitch.

Chapman avoided further damage by retiring Miguel Cabrera, Fielder and Delmon Young.

Brayan Villarreal (3-1) notched the win despite allowing a run over two innings. Jose Valverde worked a perfect ninth for his 12th save in 15 opportunities.

Zack Cozart and Devin Mesoraco hit solo home runs for the Reds, who fell to 2-4 on their nine-game homestand with their fifth loss in seven contests overall.

GAME NOTEBOOK: Cincinnati LH Bill Bray began a rehab assignment with Single-A Dayton on Saturday, recording a walk and a strikeout in one scoreless inning. Bray has not pitched since April 18 due to back and groin injuries. ... Boesch was scratched from the starting lineup after suffering a sprained right ankle on Saturday. ... Tigers IF Jhonny Peralta is expected to return to the team Tuesday. Peralta will be back from paternity leave as his wife gave birth to twin girls on Saturday.